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April 18, 2017, Vol 317, No. 15, Pages 1493-1592

In This Issue of JAMA

Highlights

Abstract Full Text
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JAMA. 2017;317(15):1493-1495. doi:10.1001/jama.2016.13086
Viewpoint

Revamping the US Federal Common RuleModernizing Human Participant Research Regulations

Abstract Full Text
JAMA. 2017;317(15):1521-1522. doi:10.1001/jama.2017.1633

In this Viewpoint, Hodge and Gostin summarize the most important 2017 updates to the US Federal Policy for the Protection of Human Subjects.

The Hyde Amendment at 40 Years and Reproductive Rights in the United StatesPerennial and Panoptic

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JAMA. 2017;317(15):1523-1524. doi:10.1001/jama.2017.2742

This Viewpoint discusses the evolution of the Hyde Amendment, which in 1976 prohibited use of medical funds to pay for abortion except when the mother’s life is endangered, and efforts since then to nullify the amendment or codify it as a federal statute.

Policing and Public Health—Strategies for Collaboration

Abstract Full Text
JAMA. 2017;317(15):1525-1526. doi:10.1001/jama.2017.1854

This Viewpoint discusses the rationale for partnerships between law enforcement and public health agencies and suggests strategies to form such partnerships to prevent and respond to violence.

Adding Protective Genetic Variants to Clinical Reporting of Genomic Screening ResultsRestoring Balance

Abstract Full Text
JAMA. 2017;317(15):1527-1528. doi:10.1001/jama.2017.1533

This Viewpoint proposes that standards for interpretation of genetic variants be expanded to include protective as well as pathogenic variants and stresses the importance of considering protective variants for assessing disease risk and guiding clinical decision making.

The DASH Diet, 20 Years Later

Abstract Full Text
JAMA. 2017;317(15):1529-1530. doi:10.1001/jama.2017.1628

This Viewpoint discusses ways to improve adherence to the Dietary Approaches to Stop Hypertension (DASH) diet, which comprises foods rich in protein and fiber, limits foods high in saturated fat and sugar, and was shown in 1997 to lower blood pressure in patients with hypertension and prehypertension.

A Piece of My Mind

The Living DonorA Tale of Money, Mania, and Clinical Mastery

Abstract Full Text
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JAMA. 2017;317(15):1531-1532. doi:10.1001/jama.2016.17221
Editorial

Disentangling Maternal Depression and Antidepressant Use During Pregnancy as Risks for Autism in Children

Abstract Full Text
JAMA. 2017;317(15):1533-1534. doi:10.1001/jama.2017.3414
Original Investigation

Effect of Oral Dexamethasone Without Immediate Antibiotics vs Placebo on Acute Sore Throat in AdultsA Randomized Clinical Trial

Abstract Full Text
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JAMA. 2017;317(15):1535-1543. doi:10.1001/jama.2017.3417

This randomized controlled trial compared the effects of a single dose of dexamethasone vs placebo on sore throat symptoms among adults with acute sore throat not requiring immediate antibiotics.

Association Between Serotonergic Antidepressant Use During Pregnancy and Autism Spectrum Disorder in Children

Abstract Full Text
JAMA. 2017;317(15):1544-1552. doi:10.1001/jama.2017.3415

This cohort study uses health administrative data from Ontario, Canada, to compare development of autism spectrum disorder in children exposed vs not exposed to serotonergic antidepressants in utero.

Associations of Maternal Antidepressant Use During the First Trimester of Pregnancy With Preterm Birth, Small for Gestational Age, Autism Spectrum Disorder, and Attention-Deficit/Hyperactivity Disorder in Offspring

Abstract Full Text
JAMA. 2017;317(15):1553-1562. doi:10.1001/jama.2017.3413

This cohort study of 1 580 629 offspring born to mothers exposed vs nonexposed to first-trimester antidepressant use compared outcome rates of preterm birth, small for gestational age, autism, and attention-deficit/hyperactivity disorder.

Comparison of Recommended Eligibility for Primary Prevention Statin Therapy Based on the US Preventive Services Task Force Recommendations vs the ACC/AHA Guidelines

Abstract Full Text
has active quiz
JAMA. 2017;317(15):1563-1567. doi:10.1001/jama.2017.3416

This study uses NHANES data to compare the numbers of US adults eligible for primary prevention statin treatment under USPSTF vs ACC/AHA guideline criteria.

From The JAMA Network

Association Between Maternal Use of SSRI Medications and Autism in Their Children

Abstract Full Text
JAMA. 2017;317(15):1568-1569. doi:10.1001/jama.2016.20614

This commentary discusses a study published in JAMA Pediatrics that reported an association between use of antidepressants, specifically selective serotonin reuptake inhibitors (SSRIs) during the second and/or third trimesters and autism spectrum disorder in children.

JAMA Professionalism

Is It Time to Retire?

Abstract Full Text
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JAMA. 2017;317(15):1570-1571. doi:10.1001/jama.2017.2230

This JAMA Professionalism article uses the example of a 70-year-old physician who has concerns about his performance to discuss physician aging and its relationship to competency in clinical medical practice.

JAMA Clinical Guidelines Synopsis

Management of Helicobacter pylori Infection

Abstract Full Text
JAMA. 2017;317(15):1572-1573. doi:10.1001/jama.2017.1949

This JAMA Clinical Guidelines Synopsis summarizes the 2016 Maastricht V/Florence Consensus Report on management of Helicobacter pylori infection.

JAMA Clinical Challenge

Woman With Yellow Palms and Soles

Abstract Full Text
JAMA. 2017;317(15):1574-1575. doi:10.1001/jama.2017.1229

A woman presented with 6 months of yellowing skin on her palms and soles 6 months after beginning to take beta carotene supplements. She had no scleral icterus; liver enzyme and bilirubin values were normal, as were results of thyroid function tests. What would you do next?

Research Letter

Diagnosis of Bacterial Infection Using a 2-Transcript Host RNA Signature in Febrile Infants 60 Days or Younger

Abstract Full Text
JAMA. 2017;317(15):1577-1578. doi:10.1001/jama.2017.1365

This study compares the diagnostic accuracy of a 2-transcript vs 66-transcript host RNA disease risk score for distinguishing bacterial from viral infection in febrile infants ≤60 days old presenting to the emergency department.

Comparative Trends in Payment Adjustments Between Safety-Net and Other Hospitals Since the Introduction of the Hospital Readmission Reduction Program and Value-Based Purchasing

Abstract Full Text
JAMA. 2017;317(15):1578-1580. doi:10.1001/jama.2017.1469

This study compares trends in Medicare payment adjustments to safety-net vs non–safety-net hospitals under Hospital Readmission Reduction Program (HRRP) and Value-Based Purchasing programs, intended to incentivize higher-quality health care.

Comment & Response

Changes in Rates of Ventilator-Associated Pneumonia

Abstract Full Text
JAMA. 2017;317(15):1580-1581. doi:10.1001/jama.2017.2411

Changes in Rates of Ventilator-Associated Pneumonia—Reply

Abstract Full Text
JAMA. 2017;317(15):1581-1582. doi:10.1001/jama.2017.2431

Factors Contributing to the Weekend Effect

Abstract Full Text
JAMA. 2017;317(15):1582. doi:10.1001/jama.2017.2424

Factors Contributing to the Weekend Effect

Abstract Full Text
JAMA. 2017;317(15):1582-1583. doi:10.1001/jama.2017.2436

Notice of Retraction and Replacement: Oostdijk et al. Effects of Decontamination of the Oropharynx and Intestinal Tract on Antibiotic Resistance in ICUs: A Randomized Clinical Trial. JAMA. 2014;312(14):1429-1437.

Abstract Full Text
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JAMA. 2017;317(15):1583-1584. doi:10.1001/jama.2017.1282

Notice of Retraction and Replacement: Oostdijk et al. Effects of Decontamination of the Oropharynx and Intestinal Tract on Antibiotic Resistance in ICUs: A Randomized Clinical Trial. JAMA. 2014;312(14):1429-1437.

Correction

Errors in Study Group Numbers and Outcome Interpretation

Abstract Full Text
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JAMA. 2017;317(15):1584. doi:10.1001/jama.2017.2972
Medical News & Perspectives

Medical Community Gathers Steam to Tackle Climate’s Health Effects

Abstract Full Text
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JAMA. 2017;317(15):1511-1513. doi:10.1001/jama.2017.0969

This Medical News article discusses how physicians can become educated and involved in strategies to combat climate-related health challenges.

The JAMA Forum

Why Replacing the ACA Has Republicans in a Tizzy

Abstract Full Text
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JAMA. 2017;317(15):1514-1515. doi:10.1001/jama.2017.3700
Global Health

Potential Cause of Nodding Syndrome Identified

Abstract Full Text
JAMA. 2017;317(15):1517. doi:10.1001/jama.2017.3089

Depression Is the Leading Cause of Disability Around the World

Abstract Full Text
JAMA. 2017;317(15):1517. doi:10.1001/jama.2017.3826

Educating Religious Leaders Increases Male Circumcision Rates in Tanzania

Abstract Full Text
JAMA. 2017;317(15):1517. doi:10.1001/jama.2017.3828
News From the Food and Drug Administration

Nocturnal Polyuria Drug Approved

Abstract Full Text
JAMA. 2017;317(15):1518. doi:10.1001/jama.2017.3344

Relief for Dust Mite Allergy

Abstract Full Text
JAMA. 2017;317(15):1518. doi:10.1001/jama.2017.3630

US-EU Drug Inspection Agreement

Abstract Full Text
JAMA. 2017;317(15):1518. doi:10.1001/jama.2017.3632
JAMA Infographic

Visualizing Health Policy

US Public Opinion on Health Care Reform, 2017

Abstract Full Text
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JAMA. 2017;317(15):1516. doi:10.1001/jama.2017.3636
The Arts and Medicine

Look. Listen. Receive.Surrendering to the Art

Abstract Full Text
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JAMA. 2017;317(15):1508-1509. doi:10.1001/jama.2017.2397

This Arts and Medicine essay discusses the parallels between the encounter of truth and beauty in art and the clinical relationship between physicians and patients.

Poetry and Medicine

Forgotten Loss

Abstract Full Text
JAMA. 2017;317(15):1586. doi:10.1001/jama.2016.19532
JAMA Revisited

The Medical Expert

Abstract Full Text
JAMA. 2017;317(15):1587. doi:10.1001/jama.2017.0644
JAMA Patient Page

Tics and Tourette Syndrome

Abstract Full Text
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JAMA. 2017;317(15):1592. doi:10.1001/jama.2017.0547
JAMA Masthead

JAMA

Abstract Full Text
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JAMA. 2017;317(15):1497-1498. doi:10.1001/jama.2016.13087
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